Many issues pertaining to implementation of the CBD require collaboration at regional or even international levels. These include regional and international agreements and treaties, regional research and monitoring activities and communication through regional and international forums.

There are a number of bilateral cooperation initiatives with several countries including all GCC countries, Jordan, Iran, Uzbekistan, Kazakhstan, Morocco, Algeria, Britain, Germany, Switzerland, France, Japan, etc.

• Saudi Arabia hosts a Thematic Centre for Protected Areas for the West/Central Asia and North Africa (WESCANA) region;
• The country hosts the Secretariat of the Regional Convention for the Protection of the Red Sea and Gulf of Aden Environment. The Kingdom is also leading an initiative to formulate a Protocol for the protection and sustainable use of the marine biodiversity of the sea area within the framework of this Convention;
• Saudi Arabia is an active participant in the Regional Convention for Cooperation on the Protection of Marine Environment;
• The Kingdom hosts the Secretariat of the Convention for the Protection of Wildlife and their Habitats in the GCC Countries;
• The Natural Resources Management Training Centre in Riyadh caters to the training needs of countries in the region as well.
• Saudi Arabia is a Party to the Convention on Migratory Species (CMS), Convention on International Trade in Endangered Species, World Heritage Convention, and is currently leading an initiative to develop an Agreement on Houbara bustard within the framework of CMS. The Kingdom also pursues the Man and Biosphere Program.